Lipid labeling offers an alternative to destructive methods and allow for measurement made in native environments without immobilization. There are three major types of lipid probes: fluorescent probe...Lipid labeling offers an alternative to destructive methods and allow for measurement made in native environments without immobilization. There are three major types of lipid probes: fluorescent probes can be used for identifying target membranes or lipids, spin-probes are useful for measuring membrane dynamics, and isotopic probes are often used for membrane composition analysis.