Capturing the time and length scale of biological processes using computational methods remains a challenge for molecular modeling as resolution is limited to the order of less than 100 ns and 10 nm i...Capturing the time and length scale of biological processes using computational methods remains a challenge for molecular modeling as resolution is limited to the order of less than 100 ns and 10 nm in all-atom detail. Coarse graining reduces the degrees of freedom of the system to achieve greater size and time scales at the expense of molecular detail to simulate biological processes currently inaccessible to all atom models.
