Near-field scanning optical microscopy(NSOM), also called scanning near-field optical microscopy(SNOM), is a scanning probe technique that overcomes the diffraction barrier in traditional far-field op...Near-field scanning optical microscopy(NSOM), also called scanning near-field optical microscopy(SNOM), is a scanning probe technique that overcomes the diffraction barrier in traditional far-field optical microscopy. Conventional optical microscopy techniques are limited by the diffraction of the light and the resolution is limited to roughly 250 nm, which make it very difficult to resolve the domains or clusters in the cellular membranes.
