Styrene maleic acid lipid particles (SMALPs) are disc-shaped lipid assemblies on the nano-scale made from the interaction of membrane bilayers and styrene maleic acid (SMA) copolymer. SMALP technology...Styrene maleic acid lipid particles (SMALPs) are disc-shaped lipid assemblies on the nano-scale made from the interaction of membrane bilayers and styrene maleic acid (SMA) copolymer. SMALP technology holds great potential as a biochemical tool as it allows solubilization of membrane bilayers and its embedded constituent into discs without any use of detergents. SMALPs are thought to be superior to other disc-forming techniques.
