Model lipid bilayers or synthetic lipid bilayers are membranes that are created in vitro. In vivo studies of lipid bilayers and the proteins embedded within them can be difficult due to the complexity...Model lipid bilayers or synthetic lipid bilayers are membranes that are created in vitro. In vivo studies of lipid bilayers and the proteins embedded within them can be difficult due to the complexity of the cellular dynamics of membranes. Model bilayers use biological membranes, along with artificial constraints, to investigate the structure and function of lipid bilayers. Supported and tethered membranes are two types of model bilayers frequently used in model studies.