Lipid “rafts” are membrane microdomains composed of higher order lipids that have tight interaction with each other relative to the “sea” of liquid phase lipids known as bulk lipids. These rafts have ...Lipid “rafts” are membrane microdomains composed of higher order lipids that have tight interaction with each other relative to the “sea” of liquid phase lipids known as bulk lipids. These rafts have been estimated to be 10-200 nm in size. Small rafts can merge to form large rafts through protein-protein and protein-lipid interactions. The rafts are important because certain membrane proteins preferentially localize to these domains and biological processes such as signal transduction occur ther