We approach thermodynamics using the Energy-Interaction Model, linking particle-based models to applications across sciences. Thermodynamics, while complex, demystifies phenomena like entropy, ∆H, and...We approach thermodynamics using the Energy-Interaction Model, linking particle-based models to applications across sciences. Thermodynamics, while complex, demystifies phenomena like entropy, ∆H, and Gibbs Energy, offering insights into systems from cells to stars. With statistical models, we address questions about phase changes, reaction energetics, and more, often making predictions from known data rather than direct experiments, illustrating thermodynamics' powerful applicability.